Figure 7.

Molecular network of upregulated genes in U373MG cells following exposure to ET-770 derivative, the compound 3. Entrez Gene IDs of 84 upregulated genes in U373MG cells following a 24 hour-exposure to the compound 3 were imported into the Functional Annotation tool of DAVID. The KEGG pathways closely related to the set of imported genes were identified. The cell cycle pathway (hsa04110), identified as the first-rank upregulated pathway (Table 2), is shown, where upregulated genes are colored by orange.