Table 3.
Associations of 25(OH)D levels and severity of albuminuria and Impaired eGFR
| |
25(OH)D < 50 nmol/L, OR (95% CI) |
|||||
|---|---|---|---|---|---|---|
| Model 1a | p | Model 2b | p | Model 3c | p | |
|
No Albuminuria |
Ref |
|
Ref |
|
Ref |
|
|
Micro-albuminuria |
2.06 (1.51-2.82) |
<0.001 |
1.80 (1.35-2.41) |
<0.001 |
1.59 (1.15-2.21) |
0.007 |
|
Macro-albuminuria |
1.99 (0.95-4.17) |
0.07 |
1.70 (0.92-3.13) |
0.09 |
1.22 (0.76-1.98) |
0.39 |
| |
25(OH)D < 50 nmol/L, OR (95% CI) |
|||||
| |
Model 1a |
|
Model 2b |
|
Model 3d |
|
|
eGFR ≥60 |
Ref |
|
Ref |
|
Ref |
|
|
eGFR 30-59 |
1.25 (0.78-2.02) |
0.34 |
0.79 (0.53-1.16) |
0.22 |
0.84 (0.56-1.26) |
0.39 |
| eGFR <30 | 9.31 (2.11-41.1) | 0.004 | 5.93 (1.20-29.2) | 0.03 | 4.46 (0.88-22.7) | 0.07 |
CI – confidence interval, OR – odds ratio.
a unadjusted.
b adjusted for age and gender.
c adjusted for age, gender, diabetes, body mass index, triglycerides, cardiovascular disease, smoking, season, glomerular filtration rate and systolic blood pressure.
d adjusted for age, gender, diabetes, cholesterol, triglycerides, body mass index, smoking, ethnicity, cardiovascular disease, albuminuria and systolic blood pressure.