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. 2004 Feb;24(4):1560–1569. doi: 10.1128/MCB.24.4.1560-1569.2004

FIG. 5.

FIG. 5.

Phenotypes observed in MEFs on Mnt knockdown are not due to general effects of expressing shRNAi. (A) Immunoblot analyses for Mnt of MEFs infected with control (MSCV-pBlueRNAi-IRES-GFP) or three different MSCV-MntRNAi-IRES-GFP-expressing retroviruses. β-Actin levels were assessed as a control. (B) MEFs expressing any of the three MSCV-MntRNAi-IRES-GFP retroviruses displayed accelerated rates of proliferation compared to MEFs expressing the MSCV-pBlueRNAi-IRES-GFP retrovirus. (C) MEFs expressing any of the three MSCV-MntRNAi-IRES-GFP retroviruses, but not those infected with the retrovirus encoding MSCV-pBlueRNAi-IRES-GFP, undergo rapid apoptosis following serum withdrawal.

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