Table 1.
Yhr087wp interacting proteins according to the TAP experiments carried out in this work
Protein | Function(1) |
---|---|
Atp7p |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
Osh7p |
Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability |
Cmk1p |
Calmodulin-dependent protein kinase; may play a role in stress response |
Cmk2p |
Calmodulin-dependent protein kinase; may play a role in stress response |
Sti1p |
Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones and activates Ssa1p ATPase activity |
Tfg1p |
TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; |
Cdc33p |
Cytoplasmic mRNA cap binding protein and translation initiation factor eIF4E; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with translation initiation factor eIF4G (Tif4631p or Tif4632p) |
Scp160p |
Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins |
Tif32p |
eIF3a subunit of the core complex of translation initiation factor 3 (eIF3), essential for translation |
Tif4631p | Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); interacts with Pab1p and with eIF4A (Tif1p); also has a role in biogenesis of the large ribosomal subunit |
(1) The description according to Saccharomyces Genome Database (SGD) is shown.