FIG. 6.

Hyaloid plexus blood vessel numbers in wt and bik^−/− mice. (A) β-Galactosidase staining of an eye from a PN7 bik^+/− pup indicates bik expression in hyaloid vessels. Shown is a lateral view of the lens with attached β-galactosidase-positive VHP. β-Galactosidase-positive PM is also evident on the anterior surface of the lens (top). No β-galactosidase activity was detected in hyaloid vessels of a control wt littermate. (B) Eyes of PN16 wt (n = 5) and bik^−/− (n = 5) mice were sectioned longitudinally and counted for each hyaloid vessel type: TVL, VHP, and pupillary PM. Vessels were counted in 12 nonconsecutive sections taken at the level of the pupil. Each data point represents the average number of vessels observed per section per eye.