Table 2.
Patient comorbidities and risk factors
| Characteristic | Reference group (n = 12,231) | Anemia group (female < 12, male < 13; n = 2991) | p value |
|---|---|---|---|
| Cardiac | |||
| Arrhythmia (not otherwise specified) | 436 | 121 | 0.210 |
| Atrial fibrillation | 263 | 89 | 0.007 |
| Cardiac valve disease | 432 | 114 | 0.462 |
| Congestive heart failure | 128 | 60 | < 0.01 |
| Coronary artery disease | 1181 | 380 | < 0.01 |
| Status postheart transplant | 2 | 1 | 0.551 |
| Hypercholesterolemia | 2127 | 436 | < 0.01 |
| Hypertension | 4987 | 2991 | < 0.01 |
| Pulmonary | |||
| Chronic obstructive pulmonary disease | 886 | 195 | 0.166 |
| Pneumonia | 117 | 44 | 0.014 |
| Sleep apnea | 401 | 108 | 0.365 |
| Tuberculosis | 26 | 13 | 0.031 |
| Renal | |||
| Renal failure | 20 | 32 | < 0.01 |
| Renal transplant | 7 | 6 | 0.016 |
| Urinary tract infection | 99 | 32 | 0.167 |
| Central nervous system | |||
| Cerebrovascular disease | 353 | 120 | 0.01 |
| Endocrine | |||
| Adrenal insufficiency | 1 | 1 | 0.280 |
| Diabetes | 986 | 405 | < 0.01 |
| Hormone replacement therapy | 242 | 46 | 0.113 |
| Thyroid disease | 1243 | 337 | 0.076 |
| Gastroenterology | |||
| Gastroesophageal reflux disease | 2252 | 604 | 0.025 |
| Irritable bowel disease | 130 | 30 | 0.773 |
| Peptic ulcer disease | 184 | 80 | < 0.01 |
| Hepatobiliary | |||
| Hepatitis A/B/C | 262 | 50 | 0.104 |
| Liver disease (not otherwise specified) | 12 | 3 | 0.973 |
| Status postliver transplant | 3 | 1 | 0.788 |
| Hematology/immune system | |||
| Antiphospho Ab Syn | 3 | 0 | 0.392 |
| Cancer (not otherwise specified) | 875 | 272 | < 0.01 |
| Coagulopathies | 148 | 53 | 0.016 |
| Deep vein thrombosis | 233 | 50 | 0.397 |
| Status post-Greenfield filter | 8 | 5 | 0.088 |
| Hemochromatosis | 13 | 7 | 0.084 |
| HIV | 17 | 2 | 0.317 |
| Systemic lupus erythematosus | 38 | 18 | 0.018 |
| Lymphoma | 14 | 7 | 0.114 |
| Metastatic cancer | 1 | 0 | 0.621 |
| Peripheral vascular disease | 72 | 31 | 0.007 |
| Thrombocytopenia | 16 | 5 | 0.631 |
| Thrombophilia | 48 | 17 | 0.186 |
| Musculoskeletal disease | |||
| Bone cancer | 5 | 0 | 0.269 |
| Osteomyelitis | 20 | 9 | 0.123 |
| Osteoporosis | 346 | 75 | 0.336 |
| Paget’s disease | 14 | 3 | 0.835 |
| Rheumatoid arthritis | 200 | 134 | < 0.01 |