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. 2012 Jul 7;470(10):2695–2701. doi: 10.1007/s11999-012-2435-z

Table 2.

Patient comorbidities and risk factors

Characteristic Reference group (n = 12,231) Anemia group (female < 12, male < 13; n = 2991) p value
Cardiac
 Arrhythmia (not otherwise specified) 436 121 0.210
 Atrial fibrillation 263 89 0.007
 Cardiac valve disease 432 114 0.462
 Congestive heart failure 128 60 < 0.01
 Coronary artery disease 1181 380 < 0.01
 Status postheart transplant 2 1 0.551
 Hypercholesterolemia 2127 436 < 0.01
 Hypertension 4987 2991 < 0.01
Pulmonary
 Chronic obstructive pulmonary disease 886 195 0.166
 Pneumonia 117 44 0.014
 Sleep apnea 401 108 0.365
 Tuberculosis 26 13 0.031
Renal
 Renal failure 20 32 < 0.01
 Renal transplant 7 6 0.016
 Urinary tract infection 99 32 0.167
Central nervous system
 Cerebrovascular disease 353 120 0.01
Endocrine
 Adrenal insufficiency 1 1 0.280
 Diabetes 986 405 < 0.01
 Hormone replacement therapy 242 46 0.113
 Thyroid disease 1243 337 0.076
Gastroenterology
 Gastroesophageal reflux disease 2252 604 0.025
 Irritable bowel disease 130 30 0.773
 Peptic ulcer disease 184 80 < 0.01
Hepatobiliary
 Hepatitis A/B/C 262 50 0.104
 Liver disease (not otherwise specified) 12 3 0.973
 Status postliver transplant 3 1 0.788
Hematology/immune system
 Antiphospho Ab Syn 3 0 0.392
 Cancer (not otherwise specified) 875 272 < 0.01
 Coagulopathies 148 53 0.016
 Deep vein thrombosis 233 50 0.397
 Status post-Greenfield filter 8 5 0.088
 Hemochromatosis 13 7 0.084
 HIV 17 2 0.317
 Systemic lupus erythematosus 38 18 0.018
 Lymphoma 14 7 0.114
 Metastatic cancer 1 0 0.621
 Peripheral vascular disease 72 31 0.007
 Thrombocytopenia 16 5 0.631
 Thrombophilia 48 17 0.186
Musculoskeletal disease
 Bone cancer 5 0 0.269
 Osteomyelitis 20 9 0.123
 Osteoporosis 346 75 0.336
 Paget’s disease 14 3 0.835
 Rheumatoid arthritis 200 134 < 0.01