Table 1.

Model Parameters and Values

Dimensions
strut dimension	a	140 µm (Bailey 2009)
strut coating thickness	δ	50 µm (Mongrain, et al. 2007)
strut embedment	Lp	no embedment ~ total embedment
coronary artery wall thickness	Lx	200 µm (Lovick and Edelman 1996)
inter-strut distance	Ly	1000 µm*
Model parameters
initial drug concentration in the coating	C0	10−5 M (Sakharov, et al. 2002)
coating drug diffusivity	D1	0.01~1 µm2/s(Mongrain, et al. 2007)
isotropic vascular drug diffusivity	D2	0.1~10 µm2/s (Levin, et al. 2004)
transmural vascular drug diffusivity	D2x	0.1~10 µm2/s
circumferential vascular drug diffusivity	D2y	1~100 D2x (Hwang and Edelman 2002)
association rate constant (binding)	ka	104 M−1s−1 (Zhang, et al. 2002)
dissociation rate constant (unbinding)	kd	0.01 s−1
resistance at perivascular boundary	Rwp	5~100 s/µm (Hwang, et al. 2001)
initial binding site concentration	S0	10−5 M (Levin, et al. 2004)
partition coefficient at the perivascular boundary	κwp	1 (Creel, et al. 2000)
partition coefficient at the coating-arterial wall interface	κcw	1 (Balakrishnan, et al. 2007)

^*estimated for an eight-strut stent in a 3-mm wide coronary artery