Table 1.
Demographic characteristics of the study population
| Total | Male | Female | Age (yr) | |
| PBC probands | 44 | 4 (9.1) | 40 (90.9) | 58.8 ± 11.8 |
| PBC FDRs | 101 | 45 (44.6) | 56 (55.4) | 40.8 ± 17.9 |
| Parents | 9 (8.9) | 5 (55.6) | 4 (44.4) | 72.8 ± 8.8 |
| Children | 69 (68.3) | 30 (43.5) | 39 (56.5) | 31.3 ± 10.6 |
| Siblings | 23 (22.8) | 10 (43.5) | 13 (56.5) | 56.7 ± 10.7 |
| AIH-1 probands | 11 | 2 (18.2) | 9 (81.8) | 48.8 ± 22.0 |
| AIH-1 FDRs | 21 | 12 (57.1) | 9 (42.9) | 37.2 ± 14.0 |
| Parents | 3 (14.3) | 1 (33.3) | 2 (66.7) | 46.0 ± 19.3 |
| Children | 13 (61.9) | 7 (53.8) | 6 (46.2) | 36.6 ± 10.3 |
| Siblings | 5 (23.8) | 4 (80) | 1 (20) | 33.6 ± 20.0 |
| PSC probands | 7 | 4 (57.1) | 3 (42.9) | 40.7 ± 9.5 |
| PSC FDRs | 19 | 9 (47.4) | 10 (52.6) | 49.9 ± 21.0 |
| Parents | 9 (47.4) | 4 (44.4) | 5 (55.6) | 67.4 ± 9.4 |
| Children | 4 (21.1) | 2 (50) | 2 (50) | 17.8 ± 2.2 |
| Siblings | 6 (31.6) | 3 (50) | 3 (50) | 45.0 ± 6.1 |
| Healthy controls | 40 | 17 (42.5) | 23 (57.5) | 43.1 ± 9.8 |
Data are shown as n (%) or mean ± SD. PBC: Primary biliary cirrhosis; AIH-1: Autoimmune hepatitis-1; PSC: Primary sclerosing cholangitis; FDRs: First-degree relatives.