Table 2.

Effect of the intervention on time from enrolment to death in cohort 1

	Intervention group			Control group			Hazard ratio (95% CI)	p value	Adjusted hazard ratio (95% CI)†	Adjustedp value
	Number of deaths	Person-years at risk	Hazard of death per 100 person-years at risk (95% CI)*	Number of deaths	Person-years at risk	Hazard of death per 100 person-years at risk (95% CI)*
Primary analysis (n=9252)	997	74 256	1·34 (1·26–1·43)	747	51 861	1·44 (1·34–1·55)	0·94 (0·76–1·15)	0·532	0·92 (0·76–1·12)	0·401
Subgroup analysis: baseline CD4 count 201–350 cells per μL (n=2283)	102	20 710	0·06 (0·03–0·10)	90	13 224	0·68 (0·55–0·84)	0·73 (0·54–1·00)‡	0·052	0·70 (0·52–0·95)§¶	0·020
Subgroup analysis: baseline CD4 count ≤200 cells per μL (n=6969)	895	53 546	1·67 (1·56–1·78)	657	38 637	1·70 (1·57–1·83)	1·00 (0·80–1·24)	0·999	0·94 (0·77–1·16)	0·577

^*Binomial exact confidence intervals.

^†Adjusted for patients' age, sex, CD4 cell count at enrolment, and record of an identity number.

^‡Interaction between group and CD4 cell count stratum p=0·050.

^§Adjusted for patients' age, sex, and record of an identity number.

^¶Interaction term between group and CD4 cell count stratum p=0·049.