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. Author manuscript; available in PMC: 2013 Feb 15.
Published in final edited form as: Clin Cancer Res. 2012 Aug 15;18(16):4266–4276. doi: 10.1158/1078-0432.CCR-11-3114

Fig.1.

Fig.1

PDA contains an abundant stroma. A Mouse PDA tissue was stained with Picrosirius Red and imaged under polarized light to visualize collagen fibres (20x magnification). B Masson’s Trichrome staining highlights connective tissue distribution in an example of mouse PDA. Collagen fibres are staining in blue with the cytoplasm appearing in red (40x magnification). C Immunohistochemistry for SPARC on murine PDA (α-SPARC polyclonal antibody, Protein tech catalogue number: 15274-1-AP, 10x magnification). D Histochemical staining of hyaluronan (biotinylated hyaluronan binding protein, Calbiochem 385911, 10x magnification) reveals pan-stromal deposition in murine PDA.