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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Neuropharmacology. 2012 Aug 7;63(7):1201–1207. doi: 10.1016/j.neuropharm.2012.07.044

Fig. 3. Effects of repeated SB-334867 (10 mg/kg) on cocaine seeking during extinction and reinstatement.

Fig. 3

Rats received daily vehicle or SB-334867 (10 mg/kg) on sessions 8–14 of abstinence and prior to the 1st–7th extinction sessions, while no treatment was given on the day of reinstatement tests. Average active lever responding is shown for: A) the average of the last 3 sessions of self-administration (SA) and over the 7 sessions of extinction, B) the last session of extinction and cue-induced reinstatement, and C) the last session of extinction and cocaine primed-reinstatement. #indicates significant differences between Veh/SB group and Veh/Veh, SB/Veh groups (p < 0.05); *indicates significant differences between groups (p < 0.05). (n = 7–8/group)