Figure 3.

Ex vivo binding of [³H]-(+)-PHNO measured (a) at 24 h following cessation of a 1-week treatment with THC or vehicle, and (b) at 1 week following cessation of a 3-weeks treatment with THC or vehicle. Data are shown as mean±SEM (n=4) in the caudate/putamen (CPu), nucleus accumbens (NAcc), ventral pallidum (VP), substantia nigra (SN), and ventral tegmental area (VTA). Significantly different from the vehicle-treated group at ^*p<0.05 and ^**p<0.01 using a mixed model repeated-measures ANOVA with a post hoc t-test.