Figure 5.

Longitudinal effect of a chronic treatment with THC (1 mg/kg/day; 21 days) or its vehicle on locomotor activity. Locomotor activity was measured as the distance travelled in meters and monitored at 30 min postinjection of THC or vehicle for 60 min. Measurements were done at baseline conditions (day 0) and after the 1st (day 1), 7th (day 7), 14th (day 14), and last (day 21) injection of THC or VEH. Data are presented as mean±SEM (n=8). Significantly different from the vehicle-treated group at ^*p<0.05, using a two-way ANOVA followed by a LSD post hoc test.