| De Novo Synapse Formation |
|
|
| Morphology |
Punctate |
Punctate and tubular structures |
| Growth Cones |
Concentrated at the base of growth cones |
Often targeted to the tips of growth cones |
| Association with Stable Varicosities |
Yes |
No |
| Accumulation at terminal varicosities |
Yes |
No. The signals of protocadherin/EGFP can be found along the entire neurites |
| Learning-Related Synapse Formation |
|
|
| Terminal Varicosities |
Dissolution of WT Dscam/EGFP aggregates |
Re-targeted to the tips of growth cones |
| New Varicosities |
Accumulation of WT Dscam/EGFP |
N/A |
