FIGURE 6:

Rab11 is required for activation of MDR activity. (A) Fold change in calcein fluorescence in Rab effector peptide–injected embryos relative to a two-cell control embryo. The average calcein fluorescence of 20 embryos (± SEM) is shown. Asterisks indicate significant differences from a two-cell control embryo (ANOVA, *, p = 0.0016, **p < 0.0001). (B) Representative egg and two-cell embryos (150 min PF) showing differences in calcein accumulation after injection with 200 μM Rab11 effector peptide.