TABLE 1:
Sequence alignment of cofilin within vertebrates.
19 23 24 28 | ||
---|---|---|
Human | Cofilin-1 | K V R K S ST P E E |
Cofilin-2 | K V R K S ST Q E E | |
Actin-depolymerizing factor | K V R K C S T P E E | |
Mouse | Cofilin-1 | K V R K S S T P E E |
Chicken | Cofilin-1 | K V R K S S T P E E |
Gecko | Cofilin-1 | K V R K C S T P E E |
Frog | Cofilin-1 | K V R H P L S P E E |
Zebrafish | Cofilin-1 | R V R L Q G T D E K |
The alignment of the conserved PKC consensus sites is shown with red letters; those residues are identified as novel phosphorylation sites by PKCα.