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. 2012 Jul 20;287(38):32246–32253. doi: 10.1074/jbc.M112.364612

FIGURE 2.

FIGURE 2.

Basal and stimulated levels of COX-1, COX-2, cPGES, and mPGES-1 mRNAs in rat pancreatic islets incubated with or without IL-1β. mRNA levels were quantified by triplicate determinations using real-time RT-PCR, and data were normalized to levels of islet COX-1 mRNA. Levels of COX-1 mRNA were similar under basal and IL-1β-stimulated conditions, whereas COX-2 mRNA levels after stimulation with IL-1β were higher than their basal levels (n = 7 pairs, p < 0.01). cPGES mRNA levels under basal and IL-1β-stimulated conditions were similar, whereas mPGES-1 mRNA levels after stimulation with IL-1β were higher than basal levels (n = 7 pairs, p < 0.02).