. 2012 Aug 29;142(10):1829–1835. doi: 10.3945/jn.112.161711

TABLE 1.

Main effect of intestinal microbiota status on uterine weight and reproductive tissue histomorphometry in female apoE-null mice after 16 wk of treatment with dietary soy and equol¹

	Microbiota status
	Nonproducer	Equol producer	P value²	Adjusted P value³
Uterine weight, mg	52.2 (49.6, 55.0)^a	45.8 (43.8, 47.9)^b	0.047	0.33
Uterine area, mm²	1.58 (1.48, 1.68)^a	1.28 (1.21, 1.35)^b	0.015	0.30
Endometrial area, mm²	0.87 (0.81, 0.94)^a	0.68 (0.64, 0.73)^b	0.014	0.30
Endometrial luminal epithelial height, μm	18.3 (17.9, 18.7)^a	17.0 (16.6, 17.4)^b	0.020	0.16
Vaginal epithelial thickness, μm	101.3 (97.3, 105.3)^a	88.3 (84.7, 91.9)^b	0.013	0.25

Values are mean (mean – SEM, mean + SEM), n = 54–59 (nonproducer) or 55–60 (equol producer). Labeled means in a row without a common letter differ, P < 0.05.

P value for main effect of intestinal microbiota status.

P value for main effect of intestinal microbiota status after adjusting for estrous cycle stage as a covariate.