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. 2001 Jun 5;98(12):6777–6782. doi: 10.1073/pnas.121169698

Figure 2.

Figure 2

NKT cell deficiency did not alter T cell proliferative capacity and T helper (Th)1/Th2 balance in NOD mice. (A) Splenocytes were tested for proliferation in response to GAD and Con A. (Background = 938 cpm; n = 4.) (B) Cytokine release from splenocytes was determined 48 h after stimulation with 10 μg/ml of GAD (n = 4, spontaneous release, IFN-γ 120 ± 36 pg/ml; IL-12, 89 ± 17 pg/ml; IL-4, undetectable). (C) Cytokine release from pancreatic-infiltrating cell was determined 48 h after stimulation with 10 μg/ml of GAD (spontaneous release, IFN-γ 188 ± 45 pg/ml; IL-12, 112 ± 26 pg/ml; IL-4, undetectable). All data represent three independent experiments with similar results.