Table 1. Most Common Amino Acids at Positions of Interest by Genotype.

Five GenBank references for each HBV genotype (A-H), used previously to identify mutations associated with O-HBV infection(21), were screened to identify the most common amino acid present at positions 103, 122, and 145 of the small HBsAg compared to the mutations associated with OHBV being examined.

Position	Mutation	A	B	C	D	E	F	G	H
103	I	M*	M	M	M	M*	M	M	M
122	R	K*	K	K*	R	R	K	K	K
145	A	G	G	G	G	G	G	G	G

^*indicates that the amino acid position was variable for the given genotype.