NR8383 cells were stimulated with A. actinomycetemcomitans for 24 hrs and cytokine expression measured via ELISA for TNF-α (A), IL-6 (B), and IL-10 (C).Following isolation and culturing for 7 days, BMMϕ cells were stimulated with A. actinomycetemcomitans for 24 hrs and ELISA analysis used to measure TNF-α (D), IL-6 (E), and IL-10 (F). Representative data of 5 separate experiments is presented. (**p<0.001, ***p<0.0001)