Table 4.
PFS (progression free survival) according to KRAS mutation for the two different treatment arms
|
PFS |
FUFOX |
CAPOX |
p-value (log rank) |
|---|---|---|---|
| n = 105 | n = 96 | HR (95% CI) | |
|
All patients |
8.2 months |
6.4 months |
0.18 0.81 (0.61-1.09) |
|
WT |
8.1months |
6.4months |
0.29 |
| |
|
|
0.82 (0.56-1.19) |
|
Codon 12 mutation |
9.9months |
7.0months |
0.12 |
| |
|
|
0.62 (0.33-1.14) |
|
Codon 13 mutation |
6.1months |
13.3months |
0.22 |
| 2.52 (0.54-11.70) |
PFS, HR hazard ratio by cox regression, CI confidence interval, WT wild type.