Figure 1.

Metabolic flux distributions in the P. pastoris during growth in glucose and glucose:methanol. Metabolic flux distributions in the P. pastoris reference strain during growth in glucose (top) and glucose:methanol (bottom) chemostat cultures at about 0.1 h⁻¹. Fluxes are normalized with respect to glucose uptake rate (% C-mol/C-mol glucose). Activities of the malic enzyme and glyoxylate pathways were found to be negligible on the basis of the METAFoR analyses. Metabolic flux data for glucose-grown P. pastoris was taken from [10].