Table 1.
Demographic and disease characteristics of patients with CVS based on disease onset
| Variables | Pediatric Onset (n-29), | Adult Onset (n-72) | p-value |
|---|---|---|---|
| Mean age at onset of symptoms(years) |
13.4±12.5 |
32.3±12.3 |
0.0001 |
| Female sex |
25 (86%) |
41 (57%) |
0.005 |
|
Race (%) |
|
|
|
| White |
25 (86%) |
54 (75%) |
0.29 |
| Black |
3 (10%) |
14 (20%) |
0.38 |
| Hispanic |
1 (4%) |
2 (3%) |
1 |
| Other |
0 |
1 (1%) |
|
|
Type of CVS |
|
|
|
| CVS plus (%) |
4 (14%) |
2 (3%) |
0.05 |
| Catamenial CVS |
5 (17%) |
5 (7%) |
0.15 |
| Sato’s CVS |
2 (7%) |
4 (6%) |
1 |
| Delay in diagnosis (months) |
124.75±85.86 |
63.53±85.23 |
0.001 |
| Coalescence |
14 (48%) |
25 (36%) |
0.25 |
|
Associated Symptoms |
Available n = 27 |
Available n = 67 |
|
| Abdominal Pain |
16 (59%) |
47 (70%) |
0.34 |
|
Co-morbid disorders |
Available n = 28 |
Available n = 68 |
|
| IBS |
9 (32%) |
18 (27%) |
0.62 |
| Anxiety |
13 (46%) |
32 (47%) |
0.19 |
| Depression |
9 (32%) |
33 (49%) |
0.18 |
| Bipolar Disorder |
1 (4%) |
1 (2%) |
0.5 |
| Migraine |
16 (55%) |
30 (43%) |
0.28 |
| Cholecystectomy |
9 (32%) |
19 (30%) |
0.81 |
|
Family History (%) |
Available n = 25 |
Available n = 64 |
|
| Family history of migraine |
16 (64%) |
41 (64%) |
1 |
|
Drug use % |
Available n = 27 |
Available n = 65 |
|
| Marijuana |
8 (30%) |
27 (42%) |
0.35 |
| Alcohol |
7 (26%) |
10 (15%) |
0.25 |
| Tobacco |
3 (12%) |
30 (46%) |
0.001 |
| Narcotics |
0 |
15 (23%) |
0.004 |
| Response to therapy | 19/20 (95%) | 47/56 (84%) | 0.27 |