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. 2012 Sep 14;7(9):e44777. doi: 10.1371/journal.pone.0044777

Figure 1. The muscles of mGHRKO mice display down-regulation of lipid oxidation genes.

Figure 1

mRNA expression of indicated genes was determined by real-time PCR in quadriceps muscles of A. 16 wk-old regular chow (RC) -fed (n = 6 mice/genotype), and B. 14wk-high-fat diet (HFD) -fed (n = 14–16/group) control (open bars) and mGHRKO mice (closed bars). Each sample was probed three times and gene expression was normalized to β-actin (A) or gapdh (B) and represented as a fold change when compared to respective control (either RC- or HFD- fed). All values are represented as mean ± S.E.M. *−p≤0.05, One-way ANOVA.