Table 5. Versican isoforms predict the clinical course on top of traditional risk factors – analysis of the whole cohort.
Whole cohort (n = 74) | |||
Creatinine at follow-up | |||
Univariate model | parameter estimate | p-value | adj R2 |
Creatinine at biopsy | 0.6372 | 0.0019 | 0.1155 |
Proteinuria at biopsy | 0.0249 | 0.7930 | <0 |
TAIF | 0.4871 | 0.1520 | 0.0150 |
II | 0.3773 | 0.2440 | 0.0053 |
GS | 0.8050 | 0.0045 | 0.0983 |
Versican V0 | 339.3458 | 0.0033 | 0.1026 |
Versican V1 | 49.9941 | 0.0006 | 0.1421 |
Creatinine at follow-up | |||
Model 1 | parameter estimate | p-value | adj R2 |
Creatinine at biopsy | 0.5004 | 0.0149 | |
GS | 0.5768 | 0.0429 | |
total | 0.0009 | 0.1619 | |
Creatinine at follow-up | |||
Model 2 | parameter estimate | p-value | adj R2 |
GS | 0.5284 | 0.0579 | |
Creatinine at biopsy | 0.4294 | 0.0342 | |
Versican V0 | 232.2049 | 0.0411 | |
total | 0.0004 | 0.2012 | |
Creatinine at follow-up | |||
Model 3 | parameter estimate | p-value | adj R2 |
GS | 0.6947 | 0.0119 | |
Creatinine at biopsy | 0.3414 | 0.0894 | |
Versican V1 | 41.2212 | 0.0052 | |
total | 0.0001 | 0.2438 | |
Creatinine at follow-up | |||
Model 4 | parameter estimate | p-value | adj R2 |
Creatinine at biopsy | 0.3364 | 0.0978 | |
GS | 0.7207 | 0.0141 | |
Versican V0 | −51.2110 | 0.7789 | |
Versican V1 | 46.5995 | 0.0552 | |
total | 0.0002 | 0.2333 |
For abbreviations see table 3 or 4.