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. 2012 Sep 14;7(9):e44771. doi: 10.1371/journal.pone.0044771

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© 2012 Kenchegowda et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A–C. Scatter plots showing the significantly affected genes in (A) PN11 Klf5CN compared with the WT corneas, (B) PN56 Klf5CN compared with the WT corneas, and (C) PN56 WT compared with PN11 WT corneas. (D). Venn representation of numbers of unique characterized genes which are differentially expressed in Klf5CN corneas vs. WT corneas at PN11 or PN56. In parentheses is the percentage of genes showing valid >2-fold changes between PN11 WT and PN56 WT samples. (E). Venn representation of the overlap between Klf4- and Klf5-target genes in PN56 corneas. (F). Venn representation of the overlap between aggregate Klf5-target genes at PN11 and PN56, and genes modulated during WT corneal maturation.