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. 2012 Sep 14;7(9):e44771. doi: 10.1371/journal.pone.0044771

Table 1. Distribution of modulated genes.

Developmental changes PN56 vs. PN11 PN11: Effects in Klf5CN vs. WT corneas
Increased Decreased Unchanged
PN56: Effects in Klf5CN vs. WT corneas Increased Increased 37 (22) 0 (0) 16 (6)
Decreased 99 (42) 1 (0) 175 (48)
Unchanged 230 (79) 1 (0) 194 (44)
Decreased Increased 0 (0) 25 (17) 47 (22)
Decreased 0 (0) 3 (1) 17 (5)
Unchanged 1 (0) 44 (29) 73 (26)
Unchanged Increased 58 (18) 31 (11) 1360 (128)
Decreased 62 (7) 55 (7) 1503 (80)
Unchanged 227 (16) 139 (48) 17,417 (304)

Numbers of unique characterized genes which are differentially expressed in Klf5CN vs. WT corneas at PN11 or at PN56 (rows) are shown. Rows are broken down according to developmental changes, i.e., differences between PN56 WT and PN11 WT corneas, as designated in the shaded column. Data sets discordant between PN11 and PN56 (i.e., increased in PN11 Klf5CN but decreased in PN56 Klf5CN, or vice versa) are too small to be meaningful. Number of genes which also show valid >2-fold changes in PN56 Klf4CN cornea are shown in parentheses.