Table 4. Top 50 genes whose expression is most decreased in PN56 Klf5CN compared with the WT corneas.
| Gene symbol | Description | Mean log intensity in WT | Mean log intensity in Klf5CN | Fold Difference |
| Klf5 | Kruppel-like factor 5 | 10.22 | 4.75 | 0.02 |
| Gldc | glycine decarboxylase | 7.88 | 4.73 | 0.11 |
| Ppp1r3c | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 10.56 | 7.63 | 0.13 |
| Gkn1 | gastrokine 1 | 7.50 | 4.59 | 0.13 |
| Cyp24a1 | cytochrome P450, family 24, subfamily a, polypeptide 1 | 7.75 | 5.06 | 0.15 |
| Enpep | glutamyl aminopeptidase | 9.38 | 6.72 | 0.16 |
| Klk11 | kallikrein related-peptidase 11 | 6.71 | 4.11 | 0.16 |
| Folr1 | folate receptor 1 (adult) | 7.79 | 5.43 | 0.20 |
| Cd55 | CD55 antigen | 6.58 | 4.25 | 0.20 |
| Dsg1a | desmoglein 1 alpha | 11.33 | 9.06 | 0.21 |
| Trpm3 | transient receptor potential cation channel, subfamily M, member 3 | 7.20 | 4.98 | 0.21 |
| Il1f5 | interleukin 1 family, member 5 (delta) | 7.78 | 5.58 | 0.22 |
| Pygl | liver glycogen phosphorylase | 9.93 | 7.74 | 0.22 |
| Ldlr | low density lipoprotein receptor | 6.63 | 4.51 | 0.23 |
| Lect1 | leukocyte cell derived chemotaxin 1 | 7.83 | 5.72 | 0.23 |
| Car3 | carbonic anhydrase 3 | 6.11 | 4.01 | 0.23 |
| Ces3 | carboxylesterase 3 | 10.11 | 8.04 | 0.24 |
| Fam184b | family with sequence similarity 184, member B | 7.56 | 5.48 | 0.24 |
| Mab21l1 | mab-21-like 1 (C. elegans) | 8.51 | 6.45 | 0.24 |
| Paqr5 | progestin and adipoQ receptor family member V | 8.08 | 6.03 | 0.24 |
| Dlg2 | discs, large homolog 2 (Drosophila) | 7.79 | 5.75 | 0.24 |
| Sorbs2 | sorbin and SH3 domain containing 2 | 9.45 | 7.41 | 0.24 |
| Myo6 | myosin VI | 7.24 | 5.21 | 0.24 |
| Tkt | transketolase | 9.65 | 7.62 | 0.25 |
| Slc14a1 | solute carrier family 14 (urea transporter), member 1 | 9.34 | 7.32 | 0.25 |
| Col4a3 | collagen, type IV, alpha 3 | 8.91 | 6.89 | 0.25 |
| Aldh1a1 | aldehyde dehydrogenase family 1, subfamily A1 | 10.12 | 8.11 | 0.25 |
| Vgll3 | vestigial like 3 (Drosophila) | 7.81 | 5.89 | 0.27 |
| Abcc9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 6.78 | 4.86 | 0.27 |
| Mmab | methylmalonic aciduria (cobalamin deficiency) type B homolog (human) | 5.80 | 3.90 | 0.27 |
| Tox | thymocyte selection-associated high mobility group box | 6.12 | 4.24 | 0.27 |
| Crygb | crystallin, gamma B | 8.29 | 6.43 | 0.27 |
| Ano4 | anoctamin 4 | 5.57 | 3.71 | 0.28 |
| Capsl | calcyphosine-like | 6.06 | 4.21 | 0.28 |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 7.11 | 5.26 | 0.28 |
| Usp19 | ubiquitin specific peptidase 19 | 6.12 | 4.27 | 0.28 |
| Ano9 | anoctamin 9 | 6.62 | 4.77 | 0.28 |
| Mt3 | metallothionein 3 | 5.17 | 3.32 | 0.28 |
| Glb1l2 | galactosidase, beta 1-like 2 | 5.75 | 3.91 | 0.28 |
| Kif26a | kinesin family member 26A | 6.71 | 4.87 | 0.28 |
| Prss32 | protease, serine, 32 | 8.46 | 6.67 | 0.29 |
| Cyp2b19 | cytochrome P450, family 2, subfamily b, polypeptide 19 | 5.36 | 3.59 | 0.29 |
| Slc4a11 | solute carrier family 4, sodium bicarbonate transporter-like, member 11 | 9.40 | 7.64 | 0.29 |
| Cryaa | crystallin, alpha A | 8.39 | 6.65 | 0.30 |
| Scrn1 | secernin 1 | 5.67 | 3.93 | 0.30 |
| Phlda2 | pleckstrin homology-like domain, family A, member 2 | 6.20 | 4.47 | 0.30 |
| Osbpl6 | oxysterol binding protein-like 6 | 6.50 | 4.77 | 0.30 |
| Prkcb | protein kinase C, beta | 8.48 | 6.77 | 0.31 |
| Fxyd4 | FXYD domain-containing ion transport regulator 4 | 7.29 | 5.59 | 0.31 |
| Ipw | imprinted gene in the Prader-Willi syndrome region | 6.07 | 4.38 | 0.31 |
Genes whose expression is also decreased in the PN11 Klf5CN corneas are shown in bold.