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. 2012 Aug 27;109(37):14906–14911. doi: 10.1073/pnas.1211976109

Fig. 4.

Fig. 4.

Fluorescence microscopy showing colocalization of chaperones with NM-YFP in ring and dot structures. DIC, differential interference contrast images. The prion fibers are labeled with YFP (NM-YFP), and the chaperones are labeled with CFP. The results show that Hsp104, the Hsp70 proteins Ssa1/2 and Sse1, and the Hsp40 protein Sis1 are all found in dots and rings.