Figure 1. NPY enhances olfactory responses in fasted rats.
(A) Schematic diagram of the experimental preparation. Turbinates were exposed in rat hemi-heads; odorant (IA, isoamyl acetate) was delivered rostrally through a Pasteur pipette (b) enclosed in a glass tube (a). The recording electrodes are represented on turbinates IIb and III. The time course of recordings and NPY (or its agonists) treatment are described on the right. (B) Typical EOG responses to IA in an overnight fasted rat, before and after treatment with mucosal solution (MS) alone (left) or containing 1 µM of NPY (right). (C) Effects of MS or MS + NPY (1 µM) treatments on the time course of EOG amplitudes in response to IA in fed (B; n = 10) and overnight fasted (C; n = 10) rats. Mean ± SEM values are expressed as a percent of the baseline responses (prior to treatment). (*P<0.05; **P<0.01; ***P<0.001).