Table 3. Comparison of tissue methylmalonic acid levels of the mouse models.* .
| Mouse genotype | Liver (nmol/g tissue) | Kidney (nmol/g tissue) | Brain (nmol/g tissue) | Muscle (nmol/g tissue) |
| Control adult ( Mut +/+) | 4.8±2.0 (15) | 9.3±6.2 (27) | 6.7±4.1 (34) | 2.3±1.1 (10) |
| MMA stop codon adult ( Mut +/+ MUT Stop+/−) | 4.0±2.0 (6) | 10.1±7.2 (6) | 7.6±3.8 (6) | 2.8±1.5 (6) |
| MMA stop codon rescue adult ( Mut−/−MUT Stop+/− MUT2h +/− ) | 4272±1322 (8) | 3492±1015 (7) | 206±109 (7) | 405±249 (7) |
*
Mice at 6 weeks old. Results presented as mean ± SEM. Number of samples in parenthesis.