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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Nat Struct Mol Biol. 2012 Aug 12;19(9):925–929. doi: 10.1038/nsmb.2358

Figure 2. Kinetochore particles bound to taxol-stabilized microtubules.

Figure 2

(a) Representative images of fragments of kinetochore particles (56 nm long) bound to taxol-stabilized microtubules reveal a rod with a kink (arrow) connected to a ring on one end and a globular domain on the opposite end. (b) Large kinetochore particles (126 nm long) bind to microtubules through globular domains and an additional extension/rod (arrow) that emanates from one of the globular domains. (c) Large kinetochore particles bind to microtubules through multiple globular domains and contain an extension that connects to a ring. Scale bar is 200 nm. (d) Two selected images of kinetochores at the tip of taxol-stabilized microtubules. Globular domains extending 50 nm from the central hub bind to the microtubules and are connected to a distal ring 50 nm further. Scale bar is 200 nm. Cartoons on the left schematize the key features of the images.