Wells of 96-well fat-bottom microtiter plates were coated with smooth LPS from several bacteria, Ra-, Rc-, Rd- and Re-LPS, monophosphoryl and diphosphoryl lipid A. Recombinant MsGlv and GFP purified from Drosophila S2 cells were diluted to 120 nM and added to the ligand-coated plates, and the binding assay was performed as described in the Materials and Methods. The figure showed specific binding of recombinant MsGlv to LPS and lipid A after subtracting the total binding of the control GFP from the total binding of MsGlv. Each bar represent the mean of three individual measurements ± SEM. Comparing binding of recombinant MsGlv to different ligands, identical letters indicate not significant difference (p>0.05), while different letters indicate significant difference (p<0.05) determined by one way ANOVA followed by a Tukey's multiple comparison test.