Table 1.
Clinical data and alpha-[11C]methyl-L-tryptophan (AMT) PET kinetic values of the 9 patients with breast cancer. Patients are listed from the lowest to the highest AMT standardized uptake values (SUV).
Patient | age (years) |
Tumor type | Tumor grade |
Tumor stage |
ER | PR | HER2/ neu |
VD’ | K1 ml/g/min |
SUV |
---|---|---|---|---|---|---|---|---|---|---|
1. | 63 | carcinosarcoma | I | IIIB | − | − | − | 0.74 | 0.14 | 2.6 |
2. | 57 | invasive microp. cc. | III | IV | + | + | − | 1.07 | 0.13 | 3.1 |
3. | 50 | carcinosarcoma | III | IIIA | − | − | − | 1.13 | 0.17 | 4.2 |
4. | 29 | invasive ductal cc. | III | IIIA | + | + | +++ | 1.23 | 0.22 | 4.7 |
5. | 59 | invasive ductal cc. | II | IIA | − | + | +++ | 1.52 | 0.23 | 5.0 |
6. | 56 | invasive ductal cc. | II | IIIA | − | − | − | 1.32 | 0.21 | 5.2 |
7. | 33 | invasive ductal cc. | III | IIIA | − | + | − | 1.45 | 0.21 | 6.5 |
8. | 60 | invasive ductal cc. | III | IIIB | − | + | − | 2.01 | 0.12 | 6.6* |
9. | 44 | invasive ductal cc.† | III | IV | + | + | − | 1.61 | 0.23 | 9.8* |
Abbreviations: microp.: micropapillary; cc: carcinoma; ER: estrogen receptors; PR: progesterone receptors; VD’: volume of distribution on PET; SUV: standardized uptake values;
patient with extensive metastases (brain, lung, liver, bone);
patients with prolonged (>20 min) AMT accumulation in tumor