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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Exp Neurol. 2012 Jul 28;237(2):444–452. doi: 10.1016/j.expneurol.2012.07.013

Figure 4.

Figure 4

Treatment with NAC decreases oxidative stress in the brains of day mice. A) NAC-treated Twi mice (NAC Twi) have significantly (p< .05) reduced brain carbonyl content compared to either untreated Twi (Twi) mice. This decreased is abolished when BMT is added to the treatment regimen (NAC+BMT-Twi) (black bars). Wildtype (NAC+BMT WT) animals that received BMT have elevated protein carbonyl content compared to untreated controls.(white bars) B) Twi mice have reduced glutathione (GSH) compared with normal controls. NAC treatment, either alone or in combination with BMT increases the GSH content of the brain to normal. * = p<0.05, ** = p<0.01, *** = p<0.005.