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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Exp Neurol. 2012 Jul 28;237(2):444–452. doi: 10.1016/j.expneurol.2012.07.013

Figure 8.

Figure 8

NAC treatment results in no clinical improvement in the Twi mouse. No significant improvements were observed in NAC (green open circles) or NAC+BMT (purple open diamonds) or BMT only (orange open triangles) treated Twi mice with respect to lifespan (A), rotarod performance (B) or body weight (C) when compared with untreated Twi mice (blue closed triangles). NAC+BMT treated WT (red closed diamonds) show a small delay in weight gain and defect in motor performance, but they quickly recover and perform similarly to untreated wild type mice (black closed circles). Animals were not tested after 35d as they could no longer remain on the stationary rotarod. Body weight and rotarod measurements were not performed for BMT-Twi animals.