Table 4.
Demographic and clinical factors that predict current smoking, alcohol consumption and excess weight: multivariate analysis
| Smokinga
[OR (95CI)]b |
Alcohola
[OR (95CI)]b |
Excess weighta
[OR (95CI)]b |
|
|---|---|---|---|
| Gender (ref: male) | |||
| Female | 0.5 (0.4–0.8) | 0.3 (0.2–0.4) | 0.6 (0.5–0.8) |
| Age (years) at diagnosis (ref: ≥65) | |||
| 25–44 | 3.4 (1.3–9.0) | 2.4 (0.9–6.6) | 1.2 (0.5–2.6) |
| 45–64 | 2.5 (1.7–3.8) | 1.9 (1.4–2.6) | 1.0 (0.7–1.3) |
| Site (ref: colon) | |||
| Rectum | 1.2 (0.8–1.8) | 0.7 (0.5–1.0) | 0.8 (0.6–1.1) |
| Stage (ref: stage I) | |||
| II | 2.1 (1.3–3.5) | 1.0 (0.7–1.4) | 1.2 (0.8–1.6) |
| III | 1.3 (0.8–2.3) | 0.9 (0.6–1.4) | 1.2 (0.8–1.6) |
| IV | 2.3 (1.0–5.2) | 0.5 (0.3–1.0) | 1.0 (0.6–1.9) |
| Time (years) since diagnosis (ref: <2 years) | |||
| 2–4.9 | 0.9 (0.5–1.8) | 1.0 (0.7–1.6) | 1.1 (0.7–1.6) |
| ≥5 | 0.6 (0.3–1.1) | 0.8 (0.5–1.4) | 0.9 (0.6–1.4) |
| SES (ref: III: highest SES) | |||
| I (lowest) | 1.8 (1.1–3.0) | 0.4 (0.2–0.5) | 1.5 (1.1–2.1) |
| II (middle) | 1.5 (1.0–2.3) | 0.9 (0.6–1.3) | 1.3 (1.0–1.7) |
| Comorbidity at diagnosis (ref: none) | |||
| Yes | 1.1 (0.7–1.6) | 0.6 (0.4–0.8) | 1.78 (1.4–2.3) |
| Chemotherapy | |||
| Yes | 0.9 (0.5–1.6) | 1.7 (1.1–2.7) | 1.5 (1.1–2.3) |
aLifestyle factors including smoking status, alcohol consumption and BMI were categorised as follows: (1) current smoking: yes or no (includes lifelong non-smokers and ex-smokers), alcohol consumption: yes and no (includes ex-consumer or never consumed alcohol) and (3) excess weight: overweight (BMI 25–29.9 kg/m2) and obese (BMI ≥ 30 kg/m2)
b OR (95CI) odds ratio (95% confidence interval) adjusted for age at diagnosis, gender, site, stage, time since diagnosis, socioeconomic status and comorbidity at diagnosis