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Determination of GY785 DR and GY785 DRS binding to transforming growth factor (TGF)-β1. The binding of GY785 DR (A) and GY785 DRS (B) to TGF-β immobilized on a research-grade CM5 chip was visualized as the change in surface plasmon resonance in the form of sensorgrams. The resulting sensorgrams were fitted using BiaEval 4.1 software. The regions used in determining equilibrium dissociation constants [Kd (M)] are shown. Abbreviation: RU, resonance unit.
