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. 2011 Aug 10;53(5):750–763. doi: 10.1002/bimj.201100052

Table 3.

Results from a simulation study comparing the mean MLE (Mean), mean asymptotic standard error (SE) and nominal 95% coverage of the estimated baseline hazard and association parameter under random and threshold censorings with model misspecification

Model log(λ)=−4.83 α=0.22


Mean SE Coverage (%) Mean SE Coverage (%)
Mild misspecification, Mean no. events/f-up=47/4359
Time-dependent covariate
Constant hazard −4.03 0.17 1.8 0.251 0.033 67.7
Joint model
Constant hazard −4.75 0.22 91.2 0.194 0.027 95.3
Two-stage model
Constant hazard (every month) −4.51 0.16 48.5 0.174 0.021 73.1
Gross misspecification, Mean no. events/f-up=101/4157
Time-dependent covariate
Constant hazard −4.01 0.16 1.0 0.251 0.021 29.6
Joint model
Constant hazard −4.68 0.21 87.2 0.197 0.019 95.1
Two-stage model
Constant hazard (every month) −4.34 0.14 8.9 0.175 0.015 57.1