Fig. 6.

ACh-induced displacements of the non-α subunits at the base of the ligand-binding domain. Superimposed cross sections through the core β-sheet densities of β, γ and δ are shown, enlarged relative to the central pentamer, with arrows to indicate the displacements of β and γ. As indicated on the pentamer, these displacements, and those of the α inner sheets (green), all point in roughly the same direction (see also Fig. S6). Black and red are for the closed- and open-class maps; contours at 1.3 σ.

ACh-induced displacements of the non-α subunits at the base of the ligand-binding domain. Superimposed cross sections through the core β-sheet densities of β, γ and δ are shown, enlarged relative to the central pentamer, with arrows to indicate the displacements of β and γ. As indicated on the pentamer, these displacements, and those of the α inner sheets (green), all point in roughly the same direction (see also Fig. S6). Black and red are for the closed- and open-class maps; contours at 1.3 σ.