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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: J Am Chem Soc. 2012 Jul 18;134(30):12732–12741. doi: 10.1021/ja3042004

Figure 4.

Figure 4

Sequences of 14 gain-of-function analogs identified in the high-throughput screen. The sequence of melittin and the variants present in the library are shown at the top. The screening results are shown at the bottom. The color code is green for conserved residues, blue for changed residues. Those that were excluded from the active variants are shown at the bottom.