TABLE 4.

Parameter Estimates for Psychiatric Phenotype and Caffeine Withdrawal

	Psychiatric disorder A	Psychiatric disorder E	With. A	With. E	Genetic correlation	Environmental correlation
GAD	0.32 (0.19–0.44)	0.68 (0.56–0.81)	0.28 (0.06–0.49)	0.72 (0.52–0.94)	0.35 (−0.12–0.99)	0.04 (−0.18–0.25)
PAN	0.32 (0.14–0.49)	0.68 (0.51–0.86)	0.27 (0.05–0.48)	0.73 (0.52–0.95)	0.10 (−0.51–0.83)	−0.09 (−0.37–0.20)
PHO	0.31 (0.20–0.43)	0.69 (0.57–0.81)	0.29 (0.07–0.49)	0.71 (0.51–0.93)	−0.11 (−0.65–0.36)	0.13 (−0.09–0.34)
MDD	0.38 (0.26–0.48)	0.62 (0.52–0.74)	0.27 (0.05–0.48)	0.73 (0.52–0.95)	0.26 (−0.16–0.85)	0.08 (−0.13–0.30)
AN	0.34 (0.02–0.60)	0.66 (0.40–0.99)	0.29 (0.07–0.49)	0.72 (0.51–0.94)	0.27 (−0.63–1.00)	0.04 (−0.37–0.46)
BN	0.50 (0.28–0.68)	0.50 (0.32–0.72)	0.28 (0.06–0.48)	0.72 (0.52–0.94)	0.32 (−0.24–1.00)	−0.04 (−0.41–0.34)

Note: Common environmental parameter fixed to zero. With. = withdrawal; GAD = generalized anxiety disorder; PAN = panic disorder; PHO = phobia; MDD = major depressive disorder; AN = anorexia nervosa; BN = bulimia nervosa; A = genetic parameter; E = unique environmental parameter.