Table 1.

2 × 2 contingency table for ORA

	In the pathway	Else	Total
Differential	40	960	1000
Else	160	8840	9000
Total	200	9800	10000

The simulated microarray contains 10000 genes of which 1000 genes are differentially expressed. The novel pathway contains 200 genes of which 40 are differential genes.