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. 2012 Oct 15;508(1):49–59. doi: 10.1016/j.gene.2012.07.041

Fig. 6.

Fig. 6

A: Location of estrogen-responsive elements (ERE) in the LRP2 genes of Gallus gallus and Homo sapiens. The magnified regions show alignments of the respective published Ensembl gene sequence (ENS) with the sequences we obtained for G. gallus (1; upper box) and H. sapiens (2; shaded lower box). The presumptive EREs are underlined and bold. In chicken, the ERE sequence is located in the promoter region of LRP2, 1659 bases upstream of the start codon we identified. The ERE in the human LRP2 gene is located in intron 38. B: Schematic representation of the localization of the four Sp1 sites relative to the ERE and the start codon in the promoter region of galline LRP2.