TABLE 3.
PUBMATRIX EVALUATION OF ELEVATED TRICUSPID REGURGITATION JET VELOCITY–DRIVEN GENES IN SICKLE CELL DISEASE ACROSS PULMONARY HYPERTENSION–RELATED SEARCH TERMS
Gene Names | Gene Symbol | PH | Vascular Remodeling | Inflammation | Cancer | Angiogenesis | Hypoxia | NO | IR |
Myosin light chain 10, regulatory | MYL10 | 1 | 2 | 3 | 14 | 2 | 5 | 6 | 0 |
Adenosine A2b receptor | ADORA2B | 27 | 4 | 88 | 51 | 17 | 50 | 31 | 25 |
Complement component 1, q subcomponent binding protein | C1QBP | 0 | 1 | 35 | 33 | 0 | 0 | 1 | 2 |
Arginine decarboxylase | ADC | 58 | 0 | 369 | 2,030 | 16 | 231 | 58 | 86 |
Proline/arginine-rich end leucine-rich repeat protein | PRELP | 0 | 1 | 1 | 2 | 0 | 0 | 0 | 0 |
SAM pointed domain containing ets transcription factor | SPDEF | 0 | 0 | 3 | 39 | 2 | 0 | 0 | 0 |
Polypeptide N-acetylgalactosaminyltransferase 13 | GALNT13 | 0 | 0 | 0 | 15 | 0 | 0 | 0 | 0 |
Solute carrier family 27, member 5 | SLC27A5 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 |
N-acetyltransferase 8-like | NAT8L | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chrom 9 open reading frame 16 | C9orf16 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Definition of abbreviations: IR = ischemia reperfusion; NO = nitric oxide; PH = pulmonary hypertension.