Table 2. Cicatrising conjunctival disorders: prevalence of clinical features at diagnosis and follow up.
| CC category (no. of eyes) | OcMMP (100) | SJS-TEN (32) | Other CC (32) | |||
|---|---|---|---|---|---|---|
| n (%) |
Diagnosis |
Follow-up |
Diagnosis |
Follow-up |
Diagnosis |
Follow-up |
| Visual acuity | ||||||
| 6/6–6/18 | 80/98 (82) | 57/71 (80) | 13/22 (59) | 10/18 (71) | 23/30 (77) | 21/26 (81) |
| 6/24–6/36 | 8/98 (9) | 5/71 (7) | 4/22 (18) | 0/18 (0) | 3/30 (10) | 2/26 (8) |
| 6/60–3/60 | 3/98 (3) | 3/71 (4) | 1/22 (5) | 0/18 (0) | 3/30 (10) | 3/26 (12) |
| <3/60 | 7/98 (7) | 6/71 (9) | 4/22 (18) | 4/18 (29) | 1/30 (3) | 0/26 (0) |
| Trichiasis | 46/100 (46) | 37/80 (46) | 2/32 (6) | 7/16 (44) | 9/32 (28) | 9/26 (35) |
| Entropion | 28/100 (28) | 19/80 (24) | 2/32 (6) | 0/16 (0) | 7/32 (22) | 3/26 (12) |
| Conjunctival inflammation | ||||||
| Absent | 26/99 (26) | 57/80 (71) | 3/32 (9) | 12/16 (75) | 3/32 (9) | 21/26 (81) |
| Mild | 33/99 (33) | 17/80 (21) | 18/32 (56) | 2/16 (13) | 16/32 (50) | 4/26 (15) |
| Moderate | 25/99 (25) | 6/80 (8) | 11/32 (34) | 2/16 (13) | 11/32 (34) | 0/26 (0) |
| Severe | 15/99 (15) | 0/80 (0) | 0/32 (0) | 0/16 (0) | 2/32 (6) | 1/26 (4) |
| Lower fornix shrinkage | ||||||
| 0–25% | 33/94 (35) | 27/76 (36) | 28/32 (88) | 9/16 (56) | 17/32 (53) | 16/24 (67) |
| 25–50% | 34/94 (36) | 19/76 (25) | 2/32 (6) | 6/16 (38) | 11/32 (34) | 6/24 (25) |
| 50–75% | 16/94 (17) | 16/76 (21) | 2/32 (6) | 0/16 (0) | 2/32 (6) | 2/24 (8) |
| 75–100% | 11/94 (12) | 14/76 (18) | 0/32 (0) | 1/16 (6) | 2/32 (6) | 0/24 (0) |
| Symblepharon | ||||||
| Absent | 14/100 (14) | 10/80 (13) | 20/32 (63) | 2/16 (13) | 9/32 (28) | 6/26 (23) |
| Plica loss only | 16/100 (16) | 10/80 (13) | 0/32 (0) | 4/16 (25) | 4/32 (13) | 1/26 (4) |
| One symblepharon | 26/100 (26) | 15/80 (19) | 8/32 (25) | 2/16 (13) | 16/32 (50) | 4/26 (15) |
| Two or more symblephara | 33/100 (33) | 35/80 (44) | 4/32 (13) | 8/16 (50) | 3/32 (9) | 13/26 (50) |
| Ankyloblepharon | 11/100 (11) | 10/80 (13) | 0/32 (0) | 0/16 (0) | 0/32 (0) | 2/26 (8) |
| Tear film | ||||||
| Normal | 26/92 (28) | 20/76 (26) | 12/32 (38) | 0/16 (0) | 12/32 (38) | 12/24 (50) |
| Reduced break-up time | 29/92 (32) | 28/76 (37) | 12/32 (38) | 8/16 (50) | 8/32 (25) | 12/24 (50) |
| Dry eye | 37/92 (40) | 28/76 (37) | 8/32 (25) | 8/16 (50) | 12/32 (38) | 0/24 (0) |
| Ocular surface keratinisation | ||||||
| No keratinisation | 81/100 (81) | 69/80 (86) | 28/32 (88) | 10/16 (63) | 29/32 (91) | 21/24 (88) |
| Partial keratinisation | 18/100 (18) | 9/80 (11) | 2/32 (6) | 4/16 (25) | 3/32 (9) | 3/24 (12) |
| Whole-surface keratinisation | 1/100 (1) | 2/80 (2) | 2/32 (6) | 2/16 (13) | 0/32 (0) | 0/24 (0) |
| Other ocular surface signs | ||||||
| Punctate keratitis | 43/100 (43) | 30/80 (38) | 8/32 (25) | 5/16 (31) | 17/32 (53) | 10/26 (38) |
| Persistent epithelial defect | 4/100 (4) | 2/80 (3) | 3/32 (9) | 4/16 (25) | 2/32 (6) | 0/26 (0) |
| Limbitis | 12/100 (12) | 3/80 (4) | 2/32 (6) | 1/16 (6) | 6/32 (19) | 3/26 (12) |
| (History of) Microbial keratitis | 12/100 (12) | 3/80 (4) | 5/32 (16) | 1/16 (6) | 5/32 (16) | 0/26 (0) |
| Central opacities/neovascularisation | 9/100 (9) | 7/80 (9) | 2/32 (6) | 4/16 (25) | 1/32 (3) | 3/26 (12) |