Table 4. Multivariate predictor for grade 3–4 intraventricular hemorrhage (IVH) on the basis of n = 149 IVH cases among 1742 datasets.
Variable | Regression coefficient | OR | 95% CI | p value | |
Intercept | –5.8446 | ||||
Gestational age <26 weeks | 3.5218 | 33.844 | 16.735 – 68.443 | <0.0001 | |
26–27 | 2.3550 | 10.538 | 5.154 – 21.545 | <0.0001 | |
28–29 | 2.0245 | 7.572 | 3.746 – 15.304 | <0.0001 | |
30–32 (reference) | |||||
P63 1-min Apgar <6 | 0.9572 | 2.604 | 1.737 – 3.904 | <0.0001 | |
N16 Early sepsis <3 days | 0.9347 | 2.546 | 1.581 – 4.101 | 0.0001 | |
P35.3 No pathological Doppler result | 0.7966 | 2.218 | 1.142 – 4.309 | 0.0187 | |
P44.2 Intrapartum tocolysis | 0.6496 | 1.915 | 1.285 – 2.853 | 0.0014 |
Validation of this logistic regression model: p = 0.59 in Hosmer-Lemeshow test; area under the ROC: AUC = 0.877 (simple reclassification) or AUC = 0.861 (bootstrap cross-validation); Nagelkerke’s R2 = 0.44.
*1 P(perinatal) and N (neonatal), data from the perinatal/neonatal data collection form; ROC, receiver operating characteristic; AUC, area under the curve; OR, odds ratio