Table 1.

Surface glycoproteins of T. cruzi with extracellular matrix binding or proteolytic activity

Protein	Host Target or Ligand	Biology	Reference(s)
gp82	mucin, unknown surface ligand	binding, signaling	[138]
gp63	fibronectin, laminin	ECM protease, binding	[139]
Penetrin (gp60)	heparan, heparan sulfate, collagen	binding	[139]
Tc-85/ gp85/TS	fibronectin, laminin, cytokeratin 18	binding, retention	[140, 141]
gp35/50	mucins	binding, signaling	[142]
gp90	unknown	inhibitor of invasion, signaling	[143]
gp30	unknown	binding	[79]
Mucins/Trans-sialidase	2,3-sialyl containing host surface glycoproteins (galectin-3)	sialidase, secreted (SAPA) immunogen	[144, 145]
Mucin p45	unknown	cardiac myocyte binding	[146]
gp83	unknown	sialidase, Ca signaling	[147]
Cruzipain	bradykinin	cysteine proteases	[148, 149]
POP Tc80 serine protease	collagen I, IV, fibronectin	ECM protease	[150, 151]