Table 2.
Signaling properties of selected T. cruzi surface glycoproteins
| Protein | Biology | Reference |
|---|---|---|
| gp82 | parasite: Ca increase, PLC dependent tyrosine phosphorylation of Tc-p175 | [144, 152] |
| gp83 | parasite: Ca increase Host: MAPK signaling | [36, 153] |
| gp30 | parasite: Ca increase | [79] |
| gp35/50 | host and parasite cAMP and calcium increase | [154-156] |
| gp90 | phosphatase, ? downregulates gp82 signaling | [157] |
| cruzipain | bradykinin signaling, calcium increase, kinin generation | [86] |
| oligopeptidase B | cytosolic, cleaves a 120 kDa substrate, secreted, direct calcium release | [91, 158] |